Sister Thomasita initially ministered as a teacher at elementary schools in Iowa, Colorado, Kansas, and Missouri. Later, she was scholastic director and formation director for the Mount St. Scholastica community. 

She taught and was advisor for the literary arts magazine in the English department at Benedictine College, as well as  alumni director and campus ministry director. Upon her retirement, she was named an emerita professor.

In addition to her passion for poetry and the psalms, she has traveled to Jordan, Israel, Syria, Italy, Ireland, Germany, Pakistan, India, Kazakhstan, England, Norway, Sweden, and Denmark, being in attendance when Wangari Maathai was awarded the Nobel Peace Prize.